Protein Details: Aquaporin TIP1-1

Protein ID

ICDB_Pro_0241

Protein Name

Aquaporin TIP1-1

Gene Name

TIP1-1; TIP1

Organism

Zea mays (Maize)

Length

250 amino acids

AlphaFoldDB

AF-O64964-F1-model_v4.pdb

Function

Water channel required to facilitate the transport of water across cell membrane. May support the rapid influx of water into vacuoles during cell expansion; permit osmotic equilibration between the cytosol and the vacuolar content and rapid transcellular water flow through living cells. Its function is impaired by Hg(2+).

Sequence

MPINRIALGSHQEVYHPGALKAAFAEFISTLIFVFAGQGSGMAFSKLTGGGPTTPAGLIAAAVAHAFALFVAVSVGANISGGHVNPAVTFGAFVGGNITLFRGLLYWVAQLLGSTVACFLLRFSTGGQATGTFGLTGVSVWEALVLEIVMTFGLVYTVYATAVDPKKGSLGTIAPIAIGFIVGANILVGGAFDGASMNPAVSFGPALVSWEWGYQWVYWVGPLIGGGLAGVIYELLFISHTHEQLPSTDY

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed in roots; shoots; leaves; tassels; ears and embryos; Expressed in meristems and zones of cell enlargement: tips of primary and lateral roots; leaf primordia; and male and female inflorescence meristems. Highly expressed in the root epidermis and endodermis; parenchyma cells surrounding mature xylem vessels in the root and the stem; phloem companion cells and a ring of cells around the phloem strand in the stem and the leaf sheath; and the basal endosperm transfer cells in developing kernels; Highly expressed in the root epidermis and endodermis; parenchyma cells surrounding mature xylem vessels in the root and the stem; phloem companion cells and a ring of cells around the phloem strand in the stem and the leaf sheath; and the basal endosperm transfer cells in developing kernels.

DOI ID

10.1104/pp.117.4.1143; 10.1093/pcp/pcg168; 10.1104/pp.117.4.1153; 10.1104/pp.125.3.1206

RefSeq

NP_001104896.1